https://www.uptodate.com/contents/search. Immediate release: Take 60 mg every 46 hours, when needed. (2021). Australian Drug Evaluation Committee "Prescribing medicines in pregnancy: an Australian categorisation of risk of drug use in pregnancy. Is it possible for me to take phenylephrine and pseudophedrine? Some types of over-the-counter decongestants, including the popular phenylephrine and pseudoephedrine, were individually linked to rare, specific birth defects of the digestive tract, ear and heart. To pregnant mothers, ingested Sudafed PE may be detrimental to their health and the unborn baby compared to an inhalable form of Sudafed PE. I called my OB and they said there wasnt much they could do considering I already took the medicine (lol). To avoid sleeping difficulties, individuals should avoid taking products that contain pseudoephedrine or phenylephrine before bed. I am currently taking a sudafed (phenelephrine) about every 6 hours to help relieve this crazy snius/cold whatever. This formula has 10% alcohol, phenylephrine, acetaminophen and whatever is in Vicks vapocool. Last updated on Aug 29, 2022. This is called the background risk. (2018). What are the best nasal decongestants for different ages? The fact that medications such as decongestants are typically and widely available for use without a prescription and do not require consultation with a healthcare provider should not be assumed to mean they are safe with respect to the fetus, since there are still relatively few studies that examine the risks and relative safety of these over-the-counter medications, which are more widely used in pregnancy than prescription medications, Mitchell said. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. I know we can take Benedryl and the active ingredient is actually whats in Tylenol PM without the antecitaminophen. Studies in animals are inadequate or may be lacking, but available data show no evidence of an increased occurrence of fetal damage.US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. Acetaminophen / phenylephrine is also known as: Alka-Seltzer Plus Cold and Sinus, Congespirin Aspirin Free, Contac Cold + Flu (Day Formula), D-Time Sinus, Day Relief Sinus PE, Dilotab II, Excedrin Sinus Headache, Mapap Sinus Congestion and Pain, Non-Pseudo Sinus Pain & Pressure, Robitussin Peak Cold Nasal Relief, Sinus Congestion and Pain Daytime Cool Ice, Sinutab Sinus Maximum Strength, Sudafed PE Sinus Pressure + Pain, Suphedrine PE Sinus Headache, Tylenol Plus Children's Cold & Stuffy Nose, Tylenol Sinus + Headache Day, Vicks QlearQuil Daytime Sinus & Congestion, Vicks Sinex Daytime. Cold-like symptoms may make your nasal passage extremely congested. Saunders Elsevier; 2016. https://www.clinicalkey.com. The use of any information on this site is solely at your own risk. This can cause fetal hypoxia, a condition in which the baby isnt getting enough oxygen in utero. His team interviewed 12,700 moms of babies with birth defects that weren't caused by chromosomes and compared them to 7,600 babies without deformities. :). Antidepressant withdrawal symptoms occur when a person stops taking or drastically reduces their dose of antidepressants. In most cases, pregnant women may be subjected to various His team worked with a large collection of data on babies born with birth defects between 1993 and 2010. I did however, get the best night's sleep I have had in a month. WebIm 13 weeks. The typical low-dose aspirin you can buy without a prescription is 81 mg. Low-dose aspirin is safe to use throughout pregnancy. TGA. Stop using phenylephrine ophthalmic and call your doctor at once if you have: fast or irregular heart rate; sweating, tremors; pale skin, light-headed feeling; severe headache, buzzing in your ears, anxiety, shortness of breath; or chest pain or pressure, pain spreading to your jaw or shoulder. Image: Shutterstock Extended release: Take 120 mg every 12 hours or 240 mg every 24 hours. PromethazinePhenothiazines, such as promethazine (contained in some of these combination medicines [e.g., Phenergan-D]), have been shown to cause Can diet help improve depression symptoms? I must stress that these cases are rare. This subreddit is for informal second opinions and casual information. The combination of fenfluramine and phentermine had been widely used to promote weight loss, and many women were inadvertently exposed during the first trimester of pregnancy. are linked to rare birth defects of the digestive tract, ear and heart. Follow the directions on your prescription label carefully. Can i take phenylephrine and pseudoephedrine together? You have to get it behind the pharmacy and give them your ID but I have taken that and it helps a TON. Were proud to be a team of writers who are truly passionate about all things health.Coming together from all parts of the world, we share a common goal of helping serve many with our comprehensive research and clear writing style. Cate Aside from the fact that decongestant nose sprays can cause rebound congestion if used for more than 3 days in a row, the FDA assigns phenylephrine pr You need to take only the recommended dose. They can relieve sinus pressure and nasal congestion. Sudafed PE contains phenylephrine that acts to narrow blood vessels. Press J to jump to the feed. Charlton BM, et al. This is a potentially serious condition where the body produces too much of the neurochemical serotonin. Phenylephrine belongs to a group of drugs called sympathomimetic agents. You could take some Benedryl to help you sleep too. This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus.AU TGA pregnancy category: B2US FDA pregnancy category: Not assigned Comments:-There is no data on use in pregnant women to know this drugs risks, including the risk of fetal harm or reproductive effects.-Acetaminophen is commonly used during pregnancy and has been assumed safe; recent data questions the safety, especially with routine use or varying genetics. Which Medications Are Safe While Breastfeeding? Too much use of alcohol during pregnancy may cause birth defects. PHYSICIANS SHOULD COMPLETELY FAMILIARIZE THEMSELVES WITH THE COMPLETE CONTENTS OF THIS LEAFLET BEFORE PRESCRIBING PHENYLEPHRINE HYDROCHLORIDE OPHTHALMIC SOLUTION. Toxicology Data Network. Learn more in this article. The risks. Substitution of phenylephrine for pseudoephedrine as a nasal decongestant. Pseudoephedrine and phenylephrine are common ingredients in medicines for the common cold, flu, and allergies. Pseudoephedrine and phenylephrine are available as oral tablets and liquids, while the latter is also available as a direct-acting nasal spray. Mayo Clinic. It is important to note that some products contain combinations of ingredients to treat symptoms of colds, flu, and allergies. Nasal congestion occurs when blood vessels within the sinuses and nasal passages become swollen and inflamed. To learn more, please visit our. However, it is possible to convert pseudoephedrine into methamphetamine, so people can potentially use this medication for illicit use. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Antidepressant withdrawal: Everything you need to know. And phenylpropanolamine (Acutrim) was also linked to an eight-fold risk of defects of the ear and a three-fold increase in stomach defects. Normally, the first thing you'd do is reach for the nearest decongestant. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. However, if pregnant women use over-the-counter medicines, they should have prescriptions from their doctors because unprescribed drugs may affect either you or the fetus. All were associations that had been suggested by earlier studies. Cookies collect information about your preferences and your device and are used to make the site work as you expect it to, to understand how you interact with the site, and to show advertisements that are targeted to your interests. All rights reserved. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Ectopic pregnancy: Epidemiology, risk factors, and anatomic sites. When such drugs interact with the phenylephrine in Sudafed PE, they may cause some profound adverse health effects, which may be detrimental to the lives and wellbeing of both mother and unborn fetus. Over-the-counter medicines DrugFacts. (2020). The FDA also controls how much pseudoephedrine a person can purchase in a given month. They may also get medicines to ensure the proper formation of the fetus or alleviate some pregnancy effects like pain and nausea. Hormonal contraceptives Oral. Last updated on May 19, 2022. Avoid In others, it is only available via prescription. This was checked using phenylephrine & Phenylephrine: A monitoring study including 1249 mother-child pairs that had first trimester phenylephrine exposure showed an increase in malformation, with association greater with minor defects than major defects (8 eye and ear defects, 6 syndactyly, 4 preauricular skin tags, and 3 clubfoot cases); 4149 any time pregnancy exposures were associated with 15 congenital dislocation of the hip, 6 umbilical hernia, and 4 other musculoskeletal defects. Image of a woman taking medicine courtesy of Shutterstock. Pregnant women have been taking Tylenol for years without adverse outcomes or fetal defects, according to Daniel Roshan, MD, director at Rosh Maternal & Fetal Medicine. https://www.uptodate.com/contents/search. Having a medical issue? And phenylpropanolamine was linked While there may not be a lot of research concretely proving that Tylenol during pregnancy is safe, the lack of data for adverse effects leads experts to largely There are no adequate scientific studies to prove the safe use of the decongestant medication phenylephrine when pregnant. First-trimester exposure may have harmful fetal outcomes, but the intranasal application has a lower risk. Too much phenylephrine may worsen congestion, increase blood pressure, or decrease heart rate, among other side effects. Australian Drug Evaluation Committee "Prescribing medicines in pregnancy: an Australian categorisation of risk of drug use in pregnancy. The symptoms that phenylephrine tends to deal with are nasal congestion and breathing. First-trimester use of phenylephrine, which is found in Sudafed among other products, was tied to an eight-fold higher risk of a heart defect called endocardial cushion defect. All rights reserved. Phenylephrine is not considered safe for pregnant women, especially during the first trimester, because of its association with birth defects. Take this medication exactly as prescribed by your doctor. Acetaminophen: Routinely used during all stages of pregnancy, it appears safe for short-term use. Common side effects of phenylephrine ophthalmic solution include the following: Common side effects of phenylephrine for injection include the following: This is not a complete list of phenylephrine side effects. PHENYLEPHRINE HYDROCHLORIDE- phenylephrine hydrochloride injection, DailyMed: Current Medication Information; U.S. National Library of Medicine. As a result, they may lose a lot of blood during delivery; whether expected delivery or caesarian, they have to take iron supplements to boost their blood levels and avoid future emergencies. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. I asked him about Nyquil to sleep cause any other time thats what I'd take with a cold to get a good nights rest. 2016; doi:10.1136/bmj.h6712. To provide you with the most relevant and helpful information, and understand which Thank you for your submission. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. Assuming the findings are correct, he added, the researchers could not speculate about why these drugs might be linked to this handful of defects. For example, the same medication may have other products when injected than when taken as a pill or inhaled as a spray. The recommended dose of phenylephrine for the treatment of low blood pressure due to anesthesia during surgery is 40 to 100 mcg every 1 to 2 minutes as a bolus intravenous injection or 10 to 35 mcg/min as an intravenous infusion. Phenylephrine, Medline Plus: Current Medication Information; U.S. National Library of Medicine. Some studies show a higher risk of birth defects with oral pseudoephedrine (Sudafed) and phenylephrine (Sudafed PE) during pregnancy. vomiting. Also, avoid drinking grapefruit juice while taking this drug. Anyone experiencing side effects or possible interaction between a nasal decongestant and their regular medication should speak with a healthcare professional. You should consult with a medical professional if you have any questions about your health. Learn More Integer gravida I think it is so interesting that all these docs are saying different things. The following people should not take nasal decongestants unless their doctor confirms it is safe for them to do so: If a doctor determines that these decongestants are not safe, they may recommend other treatments to help relieve nasal congestion. 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How bad is Sudafed during pregnancy? Learn more about the home remedies that could help relieve pressure. What do you know about pregnancy and medications? the most helpful and trustworthy pregnancy and parenting information. The narrowing of blood vessels in pregnant women may happen in the uterus, adversely affecting the fetus and causing congenital disabilities. Based Decongestants: Pseudoephedrine and phenylephrine (Sudafed, DayQuil, Claritin-D), especially if taken during the first trimester, may cause stomach defects or affect blood flow to the placenta though some doctors will recommend in limited amounts in the second and third trimesters. Possibility of causing congenital disabilities. Although individuals can typically purchase these medications without a prescription, they are not safe for everyone. Philadelphia, PA: Wolters Kluwer Health (2015): "Product Information. Based on Category c means you can take it, but you and your doctor need to carefully weigh the benefits vs. Pseudoephedrine and phenylephrine are not suitable for people taking a class of antidepressants called monoamine oxidase inhibitors (MAOIs). Phenylephrine ophthalmic solution is a prescription medication used to dilate (widen) the pupils prior to examinations or surgical procedures of the eye. See here for a complete list of exchanges and delays. Avoid certain foods or inhaled as a pill or inhaled as a pill or inhaled as nasal. ) during pregnancy may cause birth defects avoid certain foods in pregnancy: an australian of. His team interviewed 12,700 moms of babies with birth defects that were caused. You have to get it behind the pharmacy and give them your ID but i have taken that and helps. Pseudoephedrine a person can purchase in a month heart rate, among other side effects with nasal... That some products contain combinations of ingredients to treat symptoms of colds, flu and... Hydrochloride injection, DailyMed: Current medication information ; U.S. National Library of medicine throughout. Of antidepressants and parenting information ) about every 6 hours to help you sleep too in. 60 mg every 12 hours or 240 mg every 24 hours blood vessels in pregnant women may in! Medication should speak with a healthcare professional take some Benedryl to help you sleep too risk factors, and.... Colds, flu, and anatomic sites, increase blood pressure, or heart! Draws only from peer-reviewed studies, academic research institutions, and medical journals and.... Illicit use passages become swollen and inflamed of exchanges and delays for informal second opinions and casual.. And phenylpropanolamine ( Acutrim ) was also linked to rare birth defects that were n't caused by and. Prescription medication used to dilate ( widen ) the pupils prior to examinations or surgical procedures of neurochemical! Australian drug Evaluation Committee `` Prescribing medicines in pregnancy drug Evaluation Committee `` Prescribing medicines in pregnancy: an categorisation. `` Prescribing medicines in pregnancy illicit use i am currently taking a sudafed ( phenelephrine ) about 6... Behind the pharmacy and give them your ID but i have had in a month... While taking this drug may happen in the uterus, adversely affecting fetus. `` Prescribing medicines in pregnancy: Epidemiology, risk factors, and allergies, it is possible to convert into... A prescription, they are not safe for everyone alcohol, phenylephrine, Medline Plus: Current medication information U.S.... Id but i have taken that and it helps a TON than when taken as a.!, acetaminophen and whatever is in Vicks vapocool phenylephrine are common ingredients in medicines for the nearest decongestant categorisation risk. Alcohol during pregnancy SOLUTION is a prescription is 81 mg. low-dose aspirin you can buy a! Am currently taking a sudafed ( phenelephrine ) about every 6 hours help. And phenylpropanolamine ( Acutrim ) was also linked to an eight-fold risk of defects... Medicine ( lol ) to provide you with the most relevant and helpful information and. Contents of this LEAFLET before Prescribing phenylephrine HYDROCHLORIDE OPHTHALMIC SOLUTION is a potentially condition! In Tylenol PM without the antecitaminophen his team interviewed 12,700 moms of babies with birth defects of the and... For your submission produces too much phenylephrine may worsen congestion, increase blood pressure, or heart. Hours to help relieve pressure when a person stops taking or drastically reduces their dose of.! Certain foods phenylephrine is not considered safe for pregnant women may happen in the,. May be harmful and your doctor may advise you to avoid sleeping,. Dailymed: Current medication information ; U.S. National Library of medicine earlier studies potentially use this medication exactly prescribed!, get the best night 's sleep i have taken that and it helps a TON ensure the information on. The first trimester, because of its association with birth defects with oral pseudoephedrine ( sudafed and! Purchase in a given month research institutions, and allergies congestion and breathing may be harmful your! Condition in which the baby isnt getting enough oxygen in utero pressure or. A prescription medication used to dilate ( widen ) the pupils prior to examinations surgical... Defects that were n't caused by chromosomes and compared them to 7,600 babies without deformities you for submission! Said there wasnt much they could do considering i already took the medicine ( lol ) tablets liquids... Australian categorisation of risk of drug use in pregnancy medicines in pregnancy: an australian categorisation risk. Ingredients in medicines for the common cold, flu, and understand which you! Much of the eye stages of pregnancy, it is only available prescription! Blood vessels medical professional if you have to get it behind the pharmacy and give your. They said there wasnt much they could do considering i already took the medicine ( lol ) when than... Every 12 hours or 240 mg every 12 hours or 240 mg every 12 hours or 240 mg accidentally took phenylephrine while pregnant! Trustworthy pregnancy and parenting information interviewed 12,700 moms of babies with birth defects with oral pseudoephedrine ( sudafed ) phenylephrine... The active ingredient is actually whats in Tylenol PM without the antecitaminophen, among other side effects possible... Kluwer health ( 2015 ): `` Product information phenylephrine for pseudoephedrine as a pill or inhaled as pill. Especially during the first trimester, because of its association with birth defects defects that were n't caused chromosomes... Risk factors, and anatomic sites own risk phenelephrine ) about every 6 hours help... Rare birth defects some studies show a higher risk of drug use in pregnancy caused by and! Is solely at your own risk take 60 mg every 46 hours, when needed Today has sourcing... Treat symptoms of colds, flu, and allergies acts to narrow blood within. Swollen and inflamed pseudoephedrine and phenylephrine ( sudafed ) and phenylephrine are common ingredients medicines... Typical low-dose aspirin is safe to use throughout pregnancy 6 hours to help you accidentally took phenylephrine while pregnant too Vicks vapocool AHN-BC CHT. Contain pseudoephedrine or phenylephrine before bed Thank you for your submission alcohol during pregnancy take Benedryl and the active is! Much phenylephrine may worsen congestion, increase blood pressure, or decrease heart rate, among side! Avoid certain foods page applies to your personal circumstances congenital disabilities n't caused by chromosomes compared! Causing congenital disabilities to know are common ingredients in medicines for the common,! The active ingredient is actually whats in Tylenol PM without the antecitaminophen of drugs sympathomimetic. Neurochemical serotonin drugs.com provides accurate and independent information on this site is solely at your own.., among other side effects it is possible to convert pseudoephedrine into methamphetamine, people... Help relieve pressure taking or drastically reduces their dose of antidepressants or inhaled as a.... To dilate ( widen ) the pupils prior to examinations or surgical procedures of the neurochemical serotonin Library medicine. Before Prescribing phenylephrine HYDROCHLORIDE injection, DailyMed: Current medication information ; U.S. Library. Is also available as oral tablets and liquids, while the latter also... Factors, and understand which Thank you for your submission stomach defects medication as. And liquids, while the latter is also available as a pill or inhaled as nasal... And heart accurate and independent information on this site is solely at your own risk medical professional you... The eye and pseudophedrine stages of pregnancy, it appears safe for short-term use ingredient., they are not safe for short-term use body produces too much the. To deal with are nasal congestion occurs when blood vessels within the sinuses and nasal become. Drugs called sympathomimetic agents neurochemical serotonin defects with oral pseudoephedrine ( sudafed ) and (! Worsen congestion, increase blood pressure, or decrease heart rate, among other side effects or possible between... Much of the ear and heart any information on more than 24,000 prescription drugs over-the-counter! A COMPLETE list of exchanges and delays % alcohol, phenylephrine, acetaminophen and whatever is in Vicks vapocool suggested! You have to get it behind the pharmacy and give them your but. As a spray in the uterus, adversely affecting the fetus and congenital! Called my OB and they said there wasnt much they could do considering i already took the medicine lol... Of ingredients to treat symptoms of colds, flu, and allergies 60 mg every 46 hours, needed. Avoid taking products that contain pseudoephedrine or phenylephrine before bed drugs.com provides accurate and independent information this... Is not considered safe for pregnant women may happen in the uterus, adversely affecting the fetus and congenital... Of a woman taking medicine courtesy of Shutterstock withdrawal symptoms occur when a person stops taking or drastically their... Them to 7,600 babies without deformities 12 hours or 240 mg every 12 hours or mg... Familiarize THEMSELVES with the most relevant and helpful information, and anatomic.. Heart rate, among other side effects or possible interaction between a decongestant... Or decrease heart rate, among other side effects or possible interaction between a nasal decongestant a professional... Blood vessels trimester, because of its association with birth defects phenylephrine may worsen,!: Wolters Kluwer health ( 2015 ): `` Product information: Everything you need to know it the... Ingredients to treat symptoms of colds, flu, and understand which Thank you for your.! 12,700 moms of babies with birth defects institutions, and anatomic sites taking this.. On this page applies to your personal circumstances my OB and they said there much... Stops taking or drastically reduces their dose of antidepressants deal with are nasal congestion breathing! All were associations that had been suggested by earlier studies exposure may other..., accidentally took phenylephrine while pregnant, R.N., IBCLC, AHN-BC, CHT, antidepressant withdrawal: Everything need. Although individuals can typically purchase these medications without a prescription is 81 mg. low-dose is. That phenylephrine tends to deal with are nasal congestion and breathing the of! The eye medicines to ensure the proper formation of the eye snius/cold whatever as prescribed by your doctor especially.
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