Lazarus - Every time Lazarus dies, gives +21.6 temporary Damage Up, gradually fading over 1 minute. ?, Satan and The Lamb as Tainted Keeper, While held, you will be teleported to a random room everytime you pick up a coin, UNLOCK: Unlock this trinket by defeating Mother as Tainted Keeper, Allows you to pay for a devil deal with this trinket, UNLOCK: Unlock this trinket by defeating Isaac, ?? 8 Spelunker Hat. All your items and consumables are temporarily removed while in the abandoned mine, The room to access Knife Piece 2 only appears if you have Knife Piece 1 already, You can skip pressing the 3 yellow buttons if you have the ability to fly and have 2 bombs to force open the door, When combined with Knife Piece 1, can be used to stab the fleshy door in the Mausoleum II, which then leads to the Corpse floor and the Mother boss, This is a one time use item that teleports you to an alternate floor, which contains every single item in the game, The items are spread between several different rooms all on pedestals. REPENTANCE - Kidney Bean now has a bigger effect radius, no longer deals damage to the enemies it's charming, and charge time has been reduced to 1 (from 2). Stat Up becomes Stat Down), Any 'Stat down' pills you take give you a permanent +0.6 Damage Up (Horse pills +1.2), Most other pills spawn a black heart when used, including R U A Wizard?, Amnesia, Bad Trip, ?? Related: How to unlock Downpour in Binding of Isaac Repentance. ?, Satan and The Lamb as Tainted Apollyon, Gives you a red attack fly, that will charge at enemies in the same direction you are shooting, Deals damage equal to your current tear damage, Stops charging once it hits an enemy and returns to Isaac's side, UNLOCK: Unlock this trinket by defeating Mother as Tainted Apollyon, Gives a 33% chance to spawn an extra blind pedestal item in all future item rooms. Can only happen once per room, Visually this is almost identical to the Guardian Angel item, but without a face, UNLOCK: Unlock this item by beating Blue Womb (Hush) with The Lost, A white orbiting fly which deals 3 contact damage per tick to enemies, This familiar orbits Isaac at a middle length distance somewhere between Distant Admiration and Forever Alone, Item Pool: Item Room, Greed Mode Item Room, Key Beggar. 0 share; Share; How to create custom challenges in the Binding of Isaac. Demo man unlocks a card that can instantly kill any enemy, including end bosses. The item called Zodiac does not count. Unlocked from the 'Dedication' achievement (participate in 31 dailies in a row), I'm Drowsy - Slows all enemies for the rest of the current room, I'm excited!!! The angel room spawned by The Stairway item also counts, Giving money to a beggar gives a flame orbital, UNLOCK: Unlock this trinket by defeating Mother as Tainted Bethany, Upon entering each new room, this trinket has a chance to copy one of your current familiars, If you have no familiars instead it will spawn either Brother Bobby or Sister Maggy, UNLOCK: Unlock this trinket by defeating Isaac, ?? Summons Mom's foot which will stomp on a random enemy in the current room, dealing 300 damage, If no enemies are in the current room, the foot will target Isaac (and do damage if it hits), however it can be used to break rocks, Gives the player the Whore of Babylon effect for the current room, increasing damage and speed, Teleports the player to the Boss room on the current floor, *, the lost item pool, tarot, card, blue, red, If used in a Super Secret Room containing a Black Heart or Eternal Heart, it will spawn those types of hearts instead, Grants the same effect as 'My Little Unicorn', which makes Isaac invincible and deal 40 contact damage to enemies per hit, Spawns 1 bomb, 1 key, 1 coin, 1 heart, which can be random variants of each, On or below the Womb, this acts as a random teleport, since there are no shops on those floors, Spawns a Slot Machine or a Fortune Machine, Gives the player the Magic Mushroom effect, which increasing size and all stats by 1 for the current room, If you use the Strength card with 12 heart containers, it will take you down to 11 when you leave the room, Gives the player the flying effect for the current room, allowing the player to fly over obstacles in the room, This card is useless if you have any item which allows you to permanently fly, * , the lost item pool, tarot, card, grey, gray, Deals 40 damage to all enemies in the room in a similar style to the Necronomicon, * , the lost item pool, tarot, card, red, blue, Gives the Book of Belial effect for the current room, increasing damage, Spawns some troll bombs at random locations in the current room, Each bomb deals 60 damage (normal bomb damage, On or below the Womb, this acts as a random teleport, since there are no item rooms on those floors, A card with three uses: A full heal, deals 100 damage to all enemies in the current room and reveals the entire map for the current floor (Treasure Map + The Compass), Killing a Devil Beggar, Key Master, or Shell Game Beggar gives you an increased chance of finding Angel rooms instead of Devil rooms. Plus this gambling machine is simple and quick, unlike the Slot Machines of old. uses as his main mechanic, Killing or damaging enemies spawns various poops, which add to his collection. No, i don't think so. This is decided by whatever you have the least of. It also leaves a gas cloud at the place where it exploded, The bomb deals 185 damage + your tear damage on hit and leaves a damage over time poison effect that does 3 times your tear damage per tick, Synergizes with tear modifying items such as My Reflection or Tiny Planet, Has a chance to drop from the Sloth miniboss fight, Counts as 1 of 3 poison items needed towards the Bob transformation, REPENTANCE - The damage of this item was significantly boosted to 185 (from 50) in Repentance, and given the poison cloud effect. When taking damage, the cannon will break and remain broken until recharged (Recharge time: 4 rooms). Based on the Steam Workshop mod created by Scayze and Ashkait, *, eyes, eyeball, bloody, white, red, googly googley, bank shot, Upon entering a room, a skull appears over a random enemy's head, Killing the marked enemy will cause the skull to move to a different enemy, If all enemies in the room are cleared in the order they are marked, Isaac gains a random reward from one of the following: Soul heart, Key, Pill, Bomb, Nickel, +0.2 Speed, +0.5 Range, +0.5 Tears, +1 Flat damage or +1 luck, Killing enemies in the wrong order will end the streak and deny you any extra rewards, Added as part of the Afterbirth+ Booster Pack #4. by doing a victory lap), UNLOCK: Unlock this item by beating Mom's Heart on Hard Mode with Apollyon, *, grey, gray, brown, orange, steam, coffee, tea, drink, cup, When used, Compost doubles up the current number of blue flies and spiders you have, When picked up, Compost will also destroy every consumable on the ground in the current room and turn each of them into a blue fly or blue spider, If you have no pickups on the ground in the current room and no other flies or spiders, Compost will spawn 1 blue fly or blue spider, When used, this item will distort all the sprites and music, rotating graphics 90 degrees and translating them diagonally up/left, while leaving the hitbox in the same place. Reveals the location of one secret room on the minimap. The Binding of Isaac: Rebirth - Custom Challenges Guide 1 - steamlists.com. poop, pots), Counts as 1 of 3 cat items needed towards the Guppy transformation, UNLOCK: Unlock this item by defeating Mother in the Corpse II as Cain, Item Pool: Devil Room, Curse Room, Red Chest, Spawns a Keeper familiar, that shoots triple tears and follows your exact movements as you walk, The keeper has 3 health coins and can die if it takes enough damage. REPENTANCE - This item was completely reworked for Repentance and no longer forces a random dice use each time. Counts as 1 of 3 spider items needed towards the Spider Baby transformation. a bomb can become a troll bomb, or a dropped coin can become a dime, UNLOCK: Unlock this trinket by defeating Isaac, ?? You may take only one of the items, before being teleported back to where you were, It's literally every item, that includes items not in item pools like Knife Pieces, UNLOCK: Unlock this item by completing every post-it note for every character, including the Tainted characters, Gives you a robot fly familar that orbits around Isaac and fires shielded tears at incoming projectiles, Deals contact damage to enemies it touches, Counts as 1 of 3 fly items needed towards the Beelzebub transformation, Item Pool: Item Room, Key Beggar, Crane Game, When used, the Meat Cleaver will split all enemies in the room into 2 smaller versions with ~40% health each, For enemies that have multiple parts to them (e.g. blue, glow, arrow, cross, * astrology, astronomy, item room, treasure room, item room pool, cyan, black, blue, glow, n, tail, Leaves a trail of tears on the floor behind Isaac which damages enemies that walk over it for 2 damage per tick, REPENTANCE - Aquarius now synergizes with tear effects, * astrology, astronomy, item room, treasure room, item room pool, black, blue, cyan, blue, glow, The size resets when leaving the floor, UNLOCK: Unlock this item by defeating The Beast as Tainted Lazarus, A fetus familiar follows Isaac, and upon entering the Boss room on each floor, it will transform into a copy of the boss, This makes bosses a lot harder, however you now get 2 boss item drops, UNLOCK: Unlock this item by defeating Hush as Jacob & Esau, You gain two familiar demons, that stay by Isaac's side and fire shots in the same direction as you, The familiars deal roughly 40% of Isaac's damage, scaling with damage upgrades you get, They sit near and rotate around Isaac depending on which way you're firing tears. ?, Satan and The Lamb as Tainted Jacob, Gives you a familiar that follows Isaac's exact movements (similar to how Jacob & Esau work) and shoots spectral tears, Similar to Jacob and Esau, positions can be altered by running it into objects, or holding the drop button (Ctrl on Steam version), When you place a bomb, the Found Soul will drop one too, If it takes any damage, it will die and not respawn until the next floor, UNLOCK: Unlock this trinket by defeating Mother as Tainted Jacob, Everytime you use your active item, you have a chance to activate another random active item, Glowing Hourglass effect is blocked from this item, UNLOCK: Unlock this trinket by defeating Isaac, ?? THEGHOST. * item room, treasure room, item room pool, white, purple, Gives Isaac the ability to fly and spectral tears, * devil pool, devil room pool, devil deal, red, crescent, moon, drop, black, Creates 5 beams of light from the sky that deal damage equal to your tear damage + 20 to any enemies which come into contact with them, The beams have a high chance to spawn on top of enemies where possible, * item room, treasure room, item room pool, feather, white, arrow, Upon death, you respawn in the previous room as Blue Baby with three Soul hearts, This is a one time use item and all new heart containers will be soul hearts, Can be used to unlock some of Blue Baby's secrets before having the character available, * item room, treasure room, item room pool, black, grey, gray, extra life, egypt, grey, gray, Upon taking damage, you have a 20% chance to gain an invulnerability shield for 7 seconds, The chance to gain a shield is affected by your luck stat and at +27 Luck it will activate every time, UNLOCK: Unlock this item by beating the Chest with Maggy, * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, Counts as 1 of 3 mushroom items needed towards the Fun Guy transformation. 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